pentobarbital will reduce the level or effect of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.pentobarbital will decrease the level or impact of tofacitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Lack of, or reduced response to tofacitinib could happen when… Read More